Dr Glass discusses P2 smoking cessation trial results
Released
Released
Announcement PDF
ASX / MEDIA ANNOUNCEMENT
EVP R&D DR MITCHELL GLASS DISCUSS WITH BRR MEDIA DATA FROM THE
PHASE II CLINICAL TRIAL OF INV102 (NADOLOL) IN SMOKING CESSATION
Brisbane, Australia and Delaware, United States, 6 October 2015: Australian respiratory technology
company Invion Limited (ASX: IVX) is delighted to invite investors to listen to Invion’s Dr Mitchell Glass
discuss the results of the Phase II clinical trial of INV102 (nadolol) in patients trying to quit smoking,
following the successful conclusion of the study.
In this audiocast, Dr Glass discusses the following:
Phase 2 trial data demonstrates INV102 treated smokers were more likely to stop smoking
completely or dramatically reduce the number of cigarettes smoked;
Data demonstrates that INV102 is a safe and effective treatment for patients with chronic
bronchitis who are enrolled in smoking cessation programs;
Invion is preparing an FDA submission during Q4 2015 for End of Phase 2 Meeting request;
and
New data paves the way for INV102 to be developed as a novel inhaled treatment for
chronic airway diseases including asthma, COPD and cystic fibrosis.
To access the audiocast, please visit this link: http://www.brrmedia.com/event/140433
-----------------------------------------About Invion Limited
Invion is a life sciences company focussed on the development of treatments for major opportunities in
respiratory and autoimmune disease. The Group has three drug assets in development across four
development programs. INV102 (nadolol) is a beta adrenergic biased ligand targeted to reverse
mucous metaplasia in the airway epithelium treat chronic inflammatory airway diseases. A large phase
II study in smoking cessation reported successful data in Q4 2015 and feasibility for an inhaled version of
the drug is well-progressed with 3M Drug Delivery Systems. A phase II asthma study funded by the US
NIH is ongoing. INV104 (zafirlukast) is a leukotriene receptor antagonist (LTRA) that reduces
inflammation, constriction of the airways, and the build-up of mucus in the lungs. An approved oral
therapy, Invion is developing an inhaled version of the drug. INV103 (ala-Cpn10) is a modified, naturally
occurring human protein which has been proposed as a founding member of the Resolution
Associated Molecular Pattern (RAMPs) family hypothesised to maintain and restore immune
homeostasis. Invion is an ASX listed company (ASX:IVX), with its clinical headquarters in Delaware, USA.
FOR MORE INFORMATION CONTACT
Managing Director and CEO: Dr Greg Collier. P: 07 3295 0500 greg.collier@inviongroup.com
Invion Limited ABN 76 094 730 417
GPO Box 1557, Brisbane, QLD, 4001. P +61 7 3295 0500 F +61 7 3295 0599 www.inviongroup.com
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